Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400680 | 0.82 | DPP4 (0.41) | DPP4 | |
| SCHEMBL28403160 | 0.82 | DPP4 (0.41) | DPP4 | |
| SCHEMBL22484240 | 0.82 | DPP4 (0.41) | DPP4 | |
| SCHEMBL13780810 | 0.75 | DPP4 (0.36) | DPP4DPP7DPP8 | |
| SCHEMBL749409 | 0.73 | HDAC1 (0.35) | DPP4DPP7DPP8 | |
| SCHEMBL749410 | 0.73 | HDAC1 (0.35) | DPP4DPP7DPP8 | |
| SCHEMBL749408 | 0.73 | HDAC1 (0.35) | DPP4DPP7DPP8 | |
| SCHEMBL30136575 | 0.73 | HDAC1 (0.35) | DPP4DPP7DPP8 | |
| SCHEMBL440648 | 0.73 | NPSR1 (0.38) | DPP4 | |
| SCHEMBL30607053 | 0.73 | NPSR1 (0.38) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819260-B | Synthesis process of sitagliptin intermediate | 江苏阿尔法药业股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-116514656-A | Synthesis process of sitagliptin intermediate | 江苏阿尔法药业股份有限公司 | 2023-08-01 | — | — | CN | disclosed |