Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30572336 | 0.82 | L3MBTL1 (0.54) | L3MBTL1SMN1; SMN2ALDH1A1CES2CES1 | |
| SCHEMBL1123589 | 0.82 | L3MBTL1 (0.54) | L3MBTL1SMN1; SMN2ALDH1A1CES2CES1 | |
| SCHEMBL12746102 | 0.80 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2ALDH1A1CES2CES1 | |
| SCHEMBL12928720 | 0.80 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2ALDH1A1CES2CES1 | |
| SCHEMBL28403522 | 0.79 | SMN1; SMN2 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1CES2CES1 | |
| SCHEMBL25514308 | 0.78 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2ALDH1A1CES2CES1 | |
| SCHEMBL14184223 | 0.77 | SMN1; SMN2 (0.48) | L3MBTL1SMN1; SMN2ALDH1A1CES2CES1 | |
| SCHEMBL28411838 | 0.77 | SMN1; SMN2 (0.44) | L3MBTL1SMN1; SMN2ALDH1A1CES2CES1 | |
| SCHEMBL11520520 | 0.76 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1CES2CES1 | |
| SCHEMBL15630941 | 0.76 | SMN1; SMN2 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116475-A | Synthesis method of α dibromide of α -heterocyclic carbonyl compound | 中国药科大学 | 2020-05-08 | — | — | CN | disclosed |