Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 18/20 | 0.56 |
| ▸ | CCND1 | P24385 | 18/20 | 0.56 |
| ▸ | CCND3 | P30281 | 15/20 | 0.56 |
| ▸ | CCND2 | P30279 | 12/20 | 0.56 |
| ▸ | CDK2 | P24941 | 6/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.56 |
| ▸ | CDK1 | P06493 | 3/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.56 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.56 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.56 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.56 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.56 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611418 | 0.87 | CDK4 (0.54) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL28404489 | 0.87 | CDK4 (0.55) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL13202803 | 0.87 | CDK4 (0.54) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL16248282 | 0.87 | CDK4 (0.54) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL29507845 | 0.85 | CDK4 (0.52) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL4826130 | 0.85 | CDK4 (0.52) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL22553519 | 0.85 | CDK4 (0.52) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL13202797 | 0.84 | CDK4 (0.52) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL2074839 | 0.83 | CDK4 (0.51) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL29615723 | 0.83 | CDK4 (0.51) | CDK4CCND1CCND3CCND2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111265668-A | Composition comprising a histamine release-promoting substance and an inhibitory compound | 黄泳华 | 2020-06-12 | — | — | CN | disclosed |