Formic Acid

Formic Acid

SCHEMBL28403702

Clc1ccc2cc[nH]c2c1.O=CO

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.78
CMA1 P23946 1/20 0.78
F7 P08709 1/20 0.55
LTA4H P09960 1/20 0.55
F3 P13726 1/20 0.55
NR4A2 P43354 1/20 0.55
CYP2A6 P11509 2/20 0.55
ALDH1A1 P00352 2/20 0.50
TYR P14679 1/20 0.50
ENPP2 Q13822 2/20 0.49
KDM4E B2RXH2 1/20 0.49
HPGD P15428 1/20 0.49
HSD17B10 Q99714 1/20 0.49
ESR1 P03372 1/20 0.48
PYGL P06737 1/20 0.47
CHEK1 O14757 1/20 0.45
DAO P14920 1/20 0.42
CSNK2A1 P68400 1/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29990254 0.88 AHR (1.00) AHRCMA1F7LTA4HF3
SCHEMBL75475 0.88 AHR (1.00) AHRCMA1F7LTA4HF3
Methane SCHEMBL27929624 0.86 AHR (0.95) AHRCMA1F7LTA4HF3
SCHEMBL27701627 0.86 AHR (0.95) AHRCMA1F7LTA4HF3
Formic Acid SCHEMBL28408351 0.85 AHR (0.78) AHRCMA1F7LTA4HF3
Phosphoric Acid SCHEMBL27611942 0.85 AHR (0.78) AHRCMA1F7LTA4HF3
Formic Acid Methyl Ester SCHEMBL28167601 0.84 AHR (0.70) AHRCMA1F7LTA4HF3
Acetic Acid SCHEMBL9120361 0.84 AHR (0.75) AHRCMA1F7LTA4HF3
Cyanide SCHEMBL31107479 0.82 AHR (0.88) AHRCMA1F7LTA4HF3
SCHEMBL6345528 0.81 AHR (0.84) AHRCMA1F7LTA4HF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107118145-B Method for cyclizing and synthesizing indole under co-catalysis of palladium-organic nitrite 中国科学技术大学 2020-05-05 CN disclosed