Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 8/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28404124 | 1.00 | SSTR4 (0.41) | SSTR4MCHR1KEAP1SYKNAMPT | |
| SCHEMBL21112516 | 0.83 | SSTR4 (0.45) | SSTR4MCHR1KEAP1NAMPTRET | |
| SCHEMBL21112518 | 0.83 | SSTR4 (0.45) | SSTR4MCHR1KEAP1NAMPTRET | |
| SCHEMBL20908060 | 0.74 | FFAR4 (0.36) | MEN1KMT2A | |
| SCHEMBL21149380 | 0.74 | FFAR4 (0.36) | MEN1KMT2A | |
| SCHEMBL20907804 | 0.74 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL21149466 | 0.74 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL21148968 | 0.74 | MEN1 (0.41) | MEN1KMT2ACYP1A2 | |
| SCHEMBL28890357 | 0.74 | MEN1 (0.41) | MEN1KMT2ACYP1A2 | |
| SCHEMBL20908058 | 0.73 | KMT2A (0.40) | MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212832-B | 1-Benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-111212832-A | 1-benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2020-05-29 | — | — | CN | disclosed |