⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1571785 | 0.75 | — | — | |
| SCHEMBL4072312 | 0.75 | LMNA (0.35) | — | |
| SCHEMBL3328836 | 0.73 | — | — | |
| SCHEMBL1271853 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL2858115 | 0.73 | — | — | |
| SCHEMBL11255404 | 0.73 | — | — | |
| SCHEMBL2086902 | 0.73 | — | — | |
| SCHEMBL455088 | 0.71 | — | — | |
| SCHEMBL455617 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL7610656 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4537315-B2 | — | — | 2010-09-01 | — | — | JP | claimed |
| CN-101663303-A | Heteroaromatics, its preparation method with and uses thereof | SUN PIAOYANG | 2010-03-03 | — | — | CN | claimed |
| EP-1581207-A4 | BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA INC (US) | 2007-07-25 | — | — | EP | claimed |
| JP-2006510736-A | — | — | 2006-03-30 | — | — | JP | claimed |
| EP-1581207-A2 | BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES | Viropharma Incorporated (US) | 2005-10-05 | — | — | EP | claimed |
| WO-2004041201-A2 | BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA INCORPORATED (US) | 2004-05-21 | — | — | WO | claimed |
| CN-101663303-B | Heteroaromatic compounds, the preparation method and the use thereof | SUN PIAOYANG | 2012-06-27 | — | — | CN | disclosed |