SCHEMBL28404281

SCHEMBL28404281

Cc1c(C(=O)c2ccccc2)oc2cc(OCC(O)CNC(C)C)ccc12

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 3/20 0.51
ADRB1 P08588 3/20 0.51
ADRB3 P13945 2/20 0.51
CYP2D6 P10635 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28415086 0.92 MEN1 (0.52) ADRB2ADRB1ADRB3CYP2D6
SCHEMBL28402351 0.92 ADRB2 (0.50) ADRB2ADRB1ADRB3
SCHEMBL28405963 0.91 ADRB2 (0.53) ADRB2ADRB1ADRB3CYP2D6
SCHEMBL28405873 0.87 CYP2D6 (0.52) ADRB2ADRB1ADRB3CYP2D6
SCHEMBL28411240 0.84 MEN1 (0.54) ADRB2ADRB1ADRB3
SCHEMBL28417224 0.83 MEN1 (0.55) ADRB2ADRB1ADRB3
Hydrochloric Acid SCHEMBL28408119 0.83 MEN1 (0.53) ADRB2ADRB1ADRB3
Maleic Acid SCHEMBL28891132 0.82 MEN1 (0.49) ADRB2ADRB1ADRB3
SCHEMBL28413714 0.81 MEN1 (0.51) ADRB2ADRB1ADRB3
SCHEMBL11734601 0.80 PTPN1 (0.54) ADRB2ADRB1ADRB3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107827849-B 6- [ 2-hydroxy-3- (alkylamino) propoxy ] benzofuran compound and application thereof 沈阳药科大学 2020-06-02 CN claimed
CN-107827849-B 6- [ 2-hydroxy-3- (alkylamino) propoxy ] benzofuran compound and application thereof 沈阳药科大学 2020-06-02 CN disclosed