Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 14/20 | 0.81 |
| ▸ | AKR1C2 | P52895 | 14/20 | 0.81 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | GFER | P55789 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594214 | 0.89 | AKR1C3 (1.00) | AKR1C3AKR1C2MEN1KMT2ALMNA | |
| SCHEMBL30701240 | 0.89 | AKR1C3 (1.00) | AKR1C3AKR1C2MEN1KMT2ALMNA | |
| SCHEMBL6435127 | 0.86 | GRIK1 (1.00) | AKR1C3AKR1C2GRIK1MEN1KMT2A | |
| SCHEMBL10987195 | 0.86 | AKR1C3 (0.61) | AKR1C3AKR1C2GRIK1MEN1KMT2A | |
| SCHEMBL9593696 | 0.85 | AKR1C3 (0.82) | AKR1C3AKR1C2MEN1KMT2ALMNA | |
| SCHEMBL10834344 | 0.85 | AKR1C3 (0.84) | AKR1C3AKR1C2GRIK1MEN1KMT2A | |
| SCHEMBL11113166 | 0.85 | AKR1C3 (0.79) | AKR1C3AKR1C2GRIK1MEN1KMT2A | |
| SCHEMBL31060427 | 0.84 | AKR1C3 (0.72) | AKR1C3AKR1C2GRIK1MEN1KMT2A | |
| SCHEMBL6551809 | 0.84 | AKR1C3 (0.72) | AKR1C3AKR1C2GRIK1MEN1KMT2A | |
| SCHEMBL11540106 | 0.83 | AKR1C3 (0.79) | AKR1C3AKR1C2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884686-B | 10-substituted acridine-3 (10) -ketone compound, preparation method and application thereof | 中国药科大学 | 2020-06-09 | — | — | CN | disclosed |