Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 15/20 | 0.79 |
| ▸ | AKR1C2 | P52895 | 15/20 | 0.79 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848735 | 0.89 | AKR1C3 (0.64) | AKR1C3AKR1C2MEN1KMT2APKM | |
| SCHEMBL10834344 | 0.88 | AKR1C3 (0.84) | AKR1C3AKR1C2MEN1KMT2APKM | |
| SCHEMBL8130645 | 0.86 | MEN1 (0.68) | AKR1C3AKR1C2MEN1KMT2APKM | |
| SCHEMBL11603313 | 0.85 | GRIK1 (0.62) | AKR1C3AKR1C2MEN1KMT2AGRIK1 | |
| SCHEMBL28404353 | 0.85 | AKR1C3 (0.81) | AKR1C3AKR1C2MEN1KMT2APKM | |
| SCHEMBL11108122 | 0.84 | AKR1C3 (0.72) | AKR1C3AKR1C2MEN1KMT2ALMNA | |
| SCHEMBL11301337 | 0.84 | GRIK1 (0.60) | AKR1C3AKR1C2MEN1KMT2APKM | |
| SCHEMBL9595058 | 0.81 | AKR1C3 (1.00) | AKR1C3AKR1C2MEN1KMT2ALMNA | |
| SCHEMBL1308442 | 0.80 | KMT2A (1.00) | AKR1C3AKR1C2MEN1KMT2APKM | |
| SCHEMBL293867 | 0.80 | AKR1C3 (1.00) | AKR1C3AKR1C2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447453-A | 2,2'-IMINODIBENZOIC ACID | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1984-05-08 | — | — | US | claimed |