Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31601473 | 0.82 | ALOX5 (0.34) | ALOX5ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL2532156 | 0.79 | ALOX5 (0.36) | ALOX5ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL10882358 | 0.76 | ALOX5 (0.33) | ALOX5ALDH1A1HIF1ATYR | |
| SCHEMBL8891283 | 0.74 | TYR (0.49) | ALOX5ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL11660171 | 0.74 | TYR (0.49) | ALOX5ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL28411368 | 0.74 | TYR (0.45) | ALOX5ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL11202288 | 0.74 | TYR (0.49) | ALOX5ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL28898243 | 0.72 | ALOX5 (0.38) | ALOX5ALDH1A1TP53CYP3A4PTGS2 | |
| SCHEMBL22284270 | 0.71 | NPSR1 (0.37) | KDM4EPTGS2HPGD | |
| SCHEMBL688489 | 0.71 | TYR (0.45) | ALOX5ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057358-A | High-heat-resistance impact-resistance polycarbonate composition and preparation method thereof | 宁波多普达聚合物有限公司 | 2020-04-24 | — | — | CN | disclosed |