Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | UQCRB | P14927 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10801744 | 0.87 | MAPK1 (0.53) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL10797260 | 0.83 | MAPK1 (0.62) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL10803243 | 0.83 | MAPK1 (0.48) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL11152164 | 0.82 | MEN1 (0.61) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL2043906 | 0.81 | MEN1 (0.58) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL10799433 | 0.80 | MEN1 (0.55) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL28400089 | 0.78 | MAPT (0.50) | MEN1KMT2AMAPK1ALDH1A1NPC1 | |
| SCHEMBL10799904 | 0.76 | MAPT (0.52) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL9119303 | 0.75 | MEN1 (0.56) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL27083675 | 0.75 | MAPK1 (0.53) | GAAMEN1KMT2AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107915748-B | Preparation method of 4- (tert-butyl) -1-phenyl-imidazo [4,5,1-kl ] phenoxazine | 华东师范大学 | 2020-05-12 | — | — | CN | claimed |
| CN-107915748-B | Preparation method of 4- (tert-butyl) -1-phenyl-imidazo [4,5,1-kl ] phenoxazine | 华东师范大学 | 2020-05-12 | — | — | CN | disclosed |
| CN-107915748-B | Preparation method of 4- (tert-butyl) -1-phenyl-imidazo [4,5,1-kl ] phenoxazine | 华东师范大学 | 2020-05-12 | — | — | CN | disclosed |