Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11152164 | 0.80 | MEN1 (0.61) | MEN1KMT2AGAACXCR2L3MBTL1 | |
| SCHEMBL9119077 | 0.78 | MEN1 (0.57) | MEN1KMT2AGAACXCR2L3MBTL1 | |
| SCHEMBL2043906 | 0.77 | MEN1 (0.58) | MEN1KMT2AGAACXCR2L3MBTL1 | |
| SCHEMBL11474065 | 0.76 | MAPT (0.49) | MEN1KMT2AL3MBTL1POLBOPRK1 | |
| SCHEMBL28405679 | 0.75 | GAA (0.56) | MEN1KMT2AGAACXCR2L3MBTL1 | |
| SCHEMBL9120292 | 0.74 | MEN1 (0.65) | MEN1KMT2AGAACXCR2L3MBTL1 | |
| SCHEMBL11589712 | 0.73 | GPR35 (0.49) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL9119530 | 0.72 | MAPK1 (0.51) | MEN1KMT2APOLBMAPK1LMNA | |
| SCHEMBL11369321 | 0.71 | MAPT (0.50) | MEN1KMT2AL3MBTL1OPRK1MAPK1 | |
| SCHEMBL16148164 | 0.71 | RORC (0.60) | MEN1KMT2AGAACXCR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477819-B1 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1995-03-15 | — | — | EP | disclosed |
| US-5200422-A | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-04-06 | — | — | US | disclosed |
| EP-0477819-A2 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1992-04-01 | — | — | EP | disclosed |