SCHEMBL28406255

SCHEMBL28406255

Cc1cccc2c1CC(=O)C=C2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.42
GSK3A P49840 1/20 0.39
GSK3B P49841 1/20 0.39
PARP1 P09874 1/20 0.37
PARP10 Q53GL7 1/20 0.37
PARP11 Q9NR21 1/20 0.37
MAOA P21397 4/20 0.33
MAOB P27338 3/20 0.33
TYR P14679 1/20 0.33
AADAT Q8N5Z0 1/20 0.33
NOTUM Q6P988 1/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
TRPA1 O75762 2/20 0.31
ATM Q13315 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
ALDH1A1 P00352 2/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16131317 0.76 CA1 (0.38) ACHEPARP1MEN1KMT2ATRPA1
SCHEMBL4854314 0.68 SLC6A2 (0.37) ACHEPARP1PARP10PARP11NOTUM
SCHEMBL5953457 0.68 CYP2A6 (0.35) ACHEPARP1PARP10PARP11NOTUM
SCHEMBL30667121 0.68 CYP2A6 (0.35) ACHEPARP1PARP10PARP11NOTUM
SCHEMBL5954183 0.67 MEN1 (0.33) ACHEMEN1KMT2ACYP1A2CYP2A6
SCHEMBL461295 0.66 GSK3A (0.46) ACHEGSK3AGSK3BPARP1MAOA
SCHEMBL29421729 0.66 GSK3A (0.46) ACHEGSK3AGSK3BPARP1MAOA
SCHEMBL994781 0.65 CES1 (0.47) GSK3AGSK3BCYP1A2CYP2A6ALDH1A1
SCHEMBL19692682 0.65 PARP1 (0.34) ACHEPARP1PARP10PARP11AADAT
SCHEMBL1923792 0.65 CYP1A2 (0.32) ACHEPARP1PARP10PARP11CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106588772-B Heavy turpentine longifolene derivative and preparation and application thereof 广西中医药大学 2020-04-24 CN disclosed