⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7668903 | 0.98 | P2RX7 (0.50) | — | |
| Hydrochloric Acid SCHEMBL2565279 | 0.98 | P2RX7 (0.50) | — | |
| Hydrochloric Acid SCHEMBL29694336 | 0.98 | P2RX7 (0.50) | — | |
| SCHEMBL29374491 | 0.77 | — | — | |
| SCHEMBL27740389 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL2700746 | 0.77 | P2RX7 (0.52) | — | |
| SCHEMBL667511 | 0.77 | — | — | |
| SCHEMBL28562845 | 0.77 | — | — | |
| SCHEMBL12957949 | 0.77 | P2RX7 (0.47) | — | |
| Hydrochloric Acid SCHEMBL17842884 | 0.76 | P2RX7 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406412-A | TGF beta inhibitors | 里格尔药品股份有限公司 | 2017-11-28 | — | — | CN | claimed |
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | UNIMATEC CO., LTD. (JP) | 2024-07-23 | — | — | US | disclosed |
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | UNIMATEC CO., LTD. (JP) | 2024-07-23 | — | — | US | disclosed |
| US-20240051943-A1 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | INTERVET INC. (US) | 2024-02-15 | — | — | US | disclosed |
| WO-2023198140-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2023-10-19 | — | — | WO | disclosed |
| WO-2023179542-A1 | 5,8-DIHYDRO-1,7-NAPHTHYRIDINE DERIVATIVES AS GLP-1 AGONISTS FOR THE TREATMENT OF DIABETES | GASHERBRUM BIO , INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| EP-4229050-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| EP-4229049-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| CN-116547278-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-08-04 | — | — | CN | disclosed |
| WO-2022136206-A1 | A PROCESS FOR THE PREPARATION OF N-(BIS(4-METHOXYPHENYL)METHYL)-6-OXO-2-(PYRIDAZIN-3-YL)-1,6-DIHYDROPYRIMIDINE-5-CARBOXAMIDE | INTERVET INTERNATIONAL B.V. (NL) | 2022-06-30 | — | — | WO | disclosed |
| WO-2011002623-A1 | SUBSTITUTED 4-HYDROXYPYRIMIDINE-5-CARBOXAMIDES | MERCK SHARP & DOHME CORP. (US) | 2011-01-06 | — | — | WO | disclosed |
| US-7709637-B2 | 5-phenylpyrimidines, their preparation, intermediates for their preparation, and their use for controlling harmful fungi | BASF SE (DE) | 2010-05-04 | — | — | US | disclosed |
| US-20090239876-A1 | Substituted 4-Hydroxypyrimidine-5-Carboxamides | MERCK SHARP & DOHME LLC | 2009-09-24 | — | — | US | disclosed |
| CN-100488952-C | 5-phenyl pyridine, its preparation method and intermediate product and uses in controlling harmful fungus | BASF AG (DE) | 2009-05-20 | — | — | CN | disclosed |
| US-20070088026-A1 | 5-phenylpyrimidines, their preparation, intermediates for their preparation, and their use for controlling harmful fungi | METAVANTE CORPORATION | 2007-04-19 | — | — | US | disclosed |
| US-7153860-B2 | 5-Phenylpyrimidines, methods and intermediate products for the production thereof and use of the same for controlling pathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-26 | — | — | US | disclosed |
| CN-1525960-A | Lorenz Gisela | �����ɷ� | 2004-09-01 | — | — | CN | disclosed |
| US-20040116429-A1 | 5-Phenylpyrimidines, methods and intermediate products for the production thereof and use of the same for controlling pathogenic fungi | BASF SE (DE) | 2004-06-17 | — | — | US | disclosed |
| EP-1373222-A2 | 5-PHENYLPYRIMIDINE, METHODS AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002074753-A2 | 5-PHENYLPYRIMIDINE, METHODS AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-26 | — | — | WO | disclosed |