SCHEMBL28406403

SCHEMBL28406403

Clc1ccc(Cl)c(-c2nc(-c3ccncc3)[nH]c2-c2ccccc2)c1

nearest known ligand 0.70

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 18/20 0.70
MAPK12 P53778 18/20 0.70
MAPK11 Q15759 18/20 0.70
MAPK14 Q16539 18/20 0.70
RAF1 P04049 11/20 0.70
GCGR P47871 8/20 0.68
BRAF P15056 4/20 0.66
MAPK9 P45984 1/20 0.63
BRDT Q58F21 1/20 0.56
ALOX5 P09917 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28397228 0.90 MAPK13 (0.70) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL20242995 0.88 RAF1 (0.70) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL28400761 0.88 BRAF (0.60) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL31305542 0.84 MAPK13 (0.50) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL14059686 0.84 MAPK13 (0.50) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL28402841 0.82 CBFB (0.54) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL28403337 0.82 IDO1 (0.50) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL6469111 0.82 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL5921859 0.82 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL6466554 0.82 MAPK13 (0.70) MAPK13MAPK12MAPK11MAPK14RAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111057043-A Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2020-04-24 CN claimed