SCHEMBL28406429

SCHEMBL28406429

CC(C)(c1ccccc1)C(N)CC(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.41
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
KIF11 P52732 4/20 0.37
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA5A P35218 1/20 0.34
CA9 Q16790 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
TACR1 P25103 2/20 0.34
KCNN4 O15554 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19954748 0.78 TAAR1 (0.45) TAAR1MAPK1KDM4ELMNAKIF11
SCHEMBL1619121 0.78 TAAR1 (0.50) TAAR1MAPK1KDM4ELMNAKIF11
SCHEMBL1527178 0.76 TAAR1 (0.43) TAAR1ALDH1A1MAPK1KDM4ELMNA
Hydrochloric Acid SCHEMBL7066884 0.76 TAAR1 (0.48) TAAR1MAPK1KDM4ELMNAKIF11
SCHEMBL8805204 0.74 TAAR1 (0.44) TAAR1ALDH1A1TSHRMAPK1KIF11
SCHEMBL9645659 0.72 TAAR1 (0.46) TAAR1ALDH1A1MAPK1KIF11MAPT
Water SCHEMBL11571409 0.72 KIF11 (0.40) TAAR1MAPK1KDM4ELMNAKIF11
Hydrochloric Acid SCHEMBL11617495 0.70 KIF11 (0.39) TAAR1MAPK1KDM4ELMNAKIF11
Water SCHEMBL11570733 0.70 CSNK1E (0.44) TAAR1ALDH1A1KIF11
SCHEMBL20999978 0.70 TAAR1 (0.44) TAAR1ALDH1A1MAPK1LMNAKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111107745-B Fungicidal compositions 先正达参股股份有限公司 2021-12-07 CN disclosed
CN-113651754-A Fungicidal compositions 先正达参股股份有限公司 2021-11-16 CN disclosed
CN-111107745-A Fungicidal compositions 先正达参股股份有限公司 2020-05-05 CN disclosed