Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 15/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20914241 | 0.83 | MEN1 (0.42) | MAT2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL20931263 | 0.81 | MAT2A (0.43) | MAT2AKDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL20914277 | 0.76 | KDM5A (0.38) | MAT2ATSHRGAAKMT2A | |
| SCHEMBL19936241 | 0.76 | MAT2A (0.56) | MAT2AKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL19927470 | 0.75 | MAT2A (0.50) | MAT2AKDM4EALDH1A1ADORA2AHPGD | |
| SCHEMBL20913970 | 0.74 | HSD17B10 (0.47) | MAT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL20914119 | 0.74 | PLAT (0.43) | KDM4EALDH1A1GAA | |
| SCHEMBL20931303 | 0.74 | CDK5 (0.35) | MAT2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL20931257 | 0.74 | MDM2 (0.38) | MAT2AKDM4ETSHRKMT2A | |
| SCHEMBL19972091 | 0.73 | MAT2A (0.51) | MAT2AKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212839-A | Pyrazolopyrimidinone compounds and uses thereof | 艾杜罗生物科技公司 | 2020-05-29 | — | — | CN | disclosed |