Benzene

Benzene

SCHEMBL28406629

C=Cc1cccc(CC)c1.c1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.46
FAAH O00519 1/20 0.40
BCL2 P10415 1/20 0.40
HDAC4 P56524 1/20 0.38
MEF2D Q14814 1/20 0.38
PTGS2 P35354 3/20 0.38
MGLL Q99685 1/20 0.38
KIF11 P52732 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
RAPGEF4 Q8WZA2 1/20 0.36
HDAC8 Q9BY41 1/20 0.35
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15783 0.98 TP53 (0.54) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL7938067 0.90 TP53 (0.47) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL29434194 0.86 BCL2 (0.47) TP53TDP1ALDH1A1TSHRBCL2
SCHEMBL4517268 0.86 BCL2 (0.47) TP53TDP1ALDH1A1TSHRBCL2
SCHEMBL5610309 0.86 TP53 (0.43) TP53TDP1ALDH1A1TSHRFAAH
Pyrrolidine SCHEMBL5598608 0.84 TP53 (0.42) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL18010570 0.84 TP53 (0.39) TP53TDP1ALDH1A1TSHRFAAH
Piperidine SCHEMBL5598247 0.83 TP53 (0.41) TP53TDP1ALDH1A1TSHRFAAH
SCHEMBL5014924 0.83 TP53 (0.41) TP53TDP1ALDH1A1TSHRFAAH
Styrene SCHEMBL8030887 0.83 ALDH1A1 (0.64) TP53TDP1ALDH1A1TSHRHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104946006-B Functional layer forming ink, method for manufacturing light-emitting element, light-emitting device, and electronic device 精工爱普生株式会社 2022-01-04 CN disclosed
CN-107849414-B Adhesive composition, adhesive film comprising the same, and organic electronic device comprising the same 株式会社LG化学 2020-06-05 CN disclosed