Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28407858 | 0.95 | EPHX1 (0.46) | EPHX1EPHX2ANPEPRNPEPDNPEP | |
| SCHEMBL28403927 | 0.93 | EPHX1 (0.49) | EPHX1EPHX2ANPEPRNPEPPRMT1 | |
| SCHEMBL28409872 | 0.89 | ANPEP (0.44) | EPHX1ANPEPRNPEPDNPEPGAA | |
| SCHEMBL11168376 | 0.86 | EPHX1 (0.53) | EPHX1EPHX2ANPEPRNPEPDNPEP | |
| SCHEMBL22135048 | 0.79 | EPHX1 (0.61) | EPHX1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28407900 | 0.79 | EPHX1 (0.63) | EPHX1EPHX2 | |
| SCHEMBL15238241 | 0.78 | EPHX1 (0.60) | EPHX1EPHX2ANPEPRNPEPDNPEP | |
| SCHEMBL19750786 | 0.77 | EPHX1 (0.70) | EPHX1EPHX2SMN1; SMN2 | |
| SCHEMBL28417155 | 0.77 | EPHX1 (0.69) | EPHX1EPHX2SMN1; SMN2 | |
| SCHEMBL28409771 | 0.76 | EPHX1 (0.48) | EPHX1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269128-B | Synthesis method of 1,1' - (hexa-2, 4-diyne-1, 6-diyl) bis (3-alkyl urea) compound | 苏州爱玛特生物科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-111269128-A | Synthesis method of 1, 1' - (hexa-2, 4-diyne-1, 6-diyl) bis (3-alkyl urea) compound | 苏州爱玛特生物科技有限公司 | 2020-06-12 | — | — | CN | disclosed |