SCHEMBL28407757

SCHEMBL28407757

C=C(C)C(=O)OCCC[SiH2]c1cccc(OC)c1OC

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.39
▸ APEX1 P27695 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ TSHR P16473 3/20 0.38
▸ HPGD P15428 1/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ NFE2L2 Q16236 2/20 0.36
▸ ALDH1A1 P00352 3/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ LMNA P02545 2/20 0.34
▸ FFAR4 Q5NUL3 1/20 0.34
▸ THRB P10828 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28407920 0.96 POLB (0.41) POLBAPEX1HTTTDP1TSHR
SCHEMBL28401961 0.95 TSHR (0.43) POLBAPEX1HTTTDP1TSHR
SCHEMBL28407867 0.95 TSHR (0.43) POLBAPEX1HTTTDP1TSHR
SCHEMBL28407923 0.83 POLB (0.40) POLBAPEX1HTTTDP1TSHR
SCHEMBL28399390 0.83 HPGD (0.40) POLBTSHRHPGDSMN1; SMN2NFE2L2
SCHEMBL27882618 0.81 CA12 (0.44) POLBAPEX1HTTTDP1TSHR
SCHEMBL15910699 0.80 SMN1; SMN2 (0.62) POLBAPEX1HTTTDP1TSHR
SCHEMBL15910690 0.80 SMN1; SMN2 (0.57) POLBAPEX1HTTTDP1TSHR
SCHEMBL28407848 0.80 POLB (0.42) POLBAPEX1HTTTDP1TSHR
SCHEMBL28403972 0.80 ALDH1A1 (0.42) POLBTSHRHPGDSMN1; SMN2NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109716491-B Method for manufacturing field effect transistor and method for manufacturing wireless communication device 东丽株式会社 2023-06-09 — — CN disclosed
CN-109964327-B Field-effect transistor, method for manufacturing same, wireless communication device using same, and commodity label 东丽株式会社 2020-05-19 — — CN disclosed
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