Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.61 |
| ▸ | GSK3B | P49841 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | CLK2 | P49760 | 1/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TOP2A | P11388 | 4/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328397 | 0.89 | TOP2A (0.57) | KCNH2GSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL28331817 | 0.89 | TOP2A (0.60) | KCNH2GSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL14143613 | 0.86 | KCNH2 (0.62) | KCNH2GSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL29393776 | 0.86 | KDM4E (0.65) | KCNH2GSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL483223 | 0.86 | KDM4E (0.65) | KCNH2GSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL10330775 | 0.85 | KCNH2 (0.64) | KCNH2GSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL541515 | 0.85 | KDM4E (0.64) | KCNH2GSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL28424222 | 0.85 | KDM4E (0.64) | KCNH2GSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL541514 | 0.85 | KDM4E (0.64) | KCNH2GSK3BKDM4EALDH1A1HPGD | |
| SCHEMBL5704390 | 0.84 | KDM4E (0.63) | KCNH2GSK3BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112641773-A | Composition containing heterocyclic compound and use thereof | 黄泳华 | 2021-04-13 | — | — | CN | claimed |
| CN-111514125-B | Composition containing quinolone compound and edetic acid compound | 中山万汉制药有限公司 | 2021-03-23 | — | — | CN | claimed |
| CN-111514125-A | Composition containing quinolone compound and edetic acid compound | 中山万汉制药有限公司 | 2020-08-11 | — | — | CN | claimed |
| CN-111150734-A | Compositions containing mixtures of quinolinone derivatives and uses thereof | 黄泳华 | 2020-05-15 | — | — | CN | claimed |
| CN-112641773-A | Composition containing heterocyclic compound and use thereof | 黄泳华 | 2021-04-13 | — | — | CN | disclosed |
| CN-111514125-B | Composition containing quinolone compound and edetic acid compound | 中山万汉制药有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-111514125-A | Composition containing quinolone compound and edetic acid compound | 中山万汉制药有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-111150734-A | Compositions containing mixtures of quinolinone derivatives and uses thereof | 黄泳华 | 2020-05-15 | — | — | CN | disclosed |