SCHEMBL28408596

SCHEMBL28408596

CC(C)(Cl)CCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TAAR1 Q96RJ0 4/20 0.43
ATM Q13315 1/20 0.43
SLC6A2 P23975 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
CYP2A6 P11509 1/20 0.42
HTR2A P28223 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
TP53 P04637 1/20 0.40
AOC3 Q16853 1/20 0.40
LMNA P02545 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28042752 0.80 TP53 (0.41) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL5249462 0.80 ALDH1A1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL315316 0.80 ALDH1A1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL5529055 0.80 ALDH1A1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL5529047 0.80 ALDH1A1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL13851699 0.79 ALDH1A1 (0.38) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL11224549 0.78 TDP1 (0.50) ALDH1A1HPGDALOX15ALOX12CASP1
Ammonia Solution, Strong SCHEMBL11662020 0.78 ALDH1A1 (0.46) ALDH1A1HPGDALOX15ALOX12CASP1
Methylsulfanylmethane SCHEMBL28890671 0.77 ALDH1A1 (0.41) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL29223826 0.77 ALDH1A1 (0.47) ALDH1A1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117720415-A Application of Salen-Ti complex catalyst in preparation of quaternary carbon-containing compound by using halohydrocarbon 山东大学 2024-03-19 CN disclosed
CN-111285750-B Device and method for continuous flow synthesis of 1,1-dimethyl-6-tert-butyl indan 天门市德远化工科技有限公司 2022-12-06 CN disclosed
CN-111285750-A Device and method for continuous flow synthesis of 1, 1-dimethyl-6-tert-butyl indan 天门市德远化工科技有限公司 2020-06-16 CN disclosed