Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21331858 | 0.91 | KMT2A (0.40) | POLBKMT2ASLC22A12CYP2C9HIF1A | |
| SCHEMBL28418713 | 0.90 | SLC22A12 (0.40) | POLBKMT2ASLC22A12CYP2C9HIF1A | |
| SCHEMBL28408966 | 0.90 | SLC22A12 (0.41) | POLBKMT2ASLC22A12CYP2C9HIF1A | |
| SCHEMBL21331849 | 0.90 | KMT2A (0.39) | POLBKMT2ASLC22A12CYP2C9HIF1A | |
| SCHEMBL28411914 | 0.90 | KMT2A (0.39) | POLBKMT2ASLC22A12CYP2C9HIF1A | |
| SCHEMBL21331841 | 0.90 | CYP2C9 (0.52) | POLBKMT2ASLC22A12CYP2C9HIF1A | |
| SCHEMBL21350305 | 0.87 | SLC22A12 (0.57) | SLC22A12 | |
| SCHEMBL28414576 | 0.87 | SLC22A12 (0.46) | POLBKMT2ASLC22A12CYP2C9HIF1A | |
| SCHEMBL21350531 | 0.82 | KDM4E (0.38) | KMT2ASLC22A12KDM4EALDH1A1HSD17B10 | |
| SCHEMBL28415061 | 0.81 | L3MBTL1 (0.44) | POLBSLC22A12CYP2C9HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440397-B | 3- (naphthalene-1-methyl substituted) pyridine derivative and synthesis method and application thereof | 南方医科大学 | 2020-06-05 | — | — | CN | disclosed |