Epicoprosterol

Epicoprosterol

SCHEMBL28409

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4CC(O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OSBP P22059 1/20 0.78
OSBP2 Q969R2 1/20 0.78
CYP2C19 P33261 2/20 0.76
CYP2D6 P10635 1/20 0.76
ST6GAL1 P15907 2/20 0.75
INPP5D Q92835 1/20 0.74
GPBAR1 Q8TDU6 5/20 0.72
CASP7 P55210 3/20 0.72
HIF1A Q16665 3/20 0.72
TP53 P04637 2/20 0.72
MAPK1 P28482 2/20 0.72
HSD17B10 Q99714 2/20 0.72
BLM P54132 2/20 0.72
TDP1 Q9NUW8 2/20 0.72
VDR P11473 2/20 0.72
USP2 O75604 2/20 0.72
LMNA P02545 2/20 0.72
CYP3A4 P08684 2/20 0.72
MDM4 O15151 1/20 0.72
MAPT P10636 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Epicoprosterol SCHEMBL12607072 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL16867279 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL12453190 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL12806627 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL24632942 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL11380074 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL25267973 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL11391325 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL21000320 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL22018677 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9799 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410758-B1 None US claimed
US-20260139254-A1 INTERFERING RNA FOR INHIBITING TOP1 GENE EXPRESSION AND USE THEREOF JENKEM TECH CO LTD BEIJING (CN) 2026-05-21 US claimed
EP-4743437-A1 DIESTER LIPIDS, LIPID NANOPARTICLE CONTAINING DIESTER LIPIDS, AND FORMULATIONS THEREOF Providence Therapeutics Holdings Inc. (CA) 2026-05-20 EP claimed
CN-122059896-A Ionizable lipid gene vector and organ selective regulation method 南开大学 2026-05-19 CN claimed
CN-122070276-A Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same 人类生物科学股份有限公司 2026-05-19 CN claimed
CN-118141102-B Compound natural antioxidant, compound grease, antioxidant preparation and application thereof 江苏瀚康生物科技有限公司 2026-05-15 CN claimed
EP-4739687-A1 STABLE PALIPERIDONE PALMITATE COMPOSITION USING THERMAL TREATMENT Eugia Pharma Specialities Limited (IN) 2026-05-13 EP claimed
EP-4737436-A1 CATIONIC LIPID CONTAINING TWO TERTIARY AMINE GROUPS, AND USE THEREOF Xiamen Sinopeg Biotech Co., Ltd (CN) 2026-05-06 EP claimed
EP-4731258-A1 LIPID NANOPARTICLES CONTAINING DISULFIDE LIPIDS AND FORMULATIONS THEREOF Providence Therapeutics Holdings Inc. (CA) 2026-04-29 EP claimed
EP-4554981-B1 SYNTHETIC HEXASACCHARIDES MIMICS OF HEPARIN SHOWING HEPARANASE INHIBITION ACTIVITY CENTRO ALTA TECNOLOGIA ST DI RICERCHE CHIMICHE E BIOCHIMICHE G RONZONI S R L (IT) 2026-04-22 EP claimed
WO-1986000066-A1 N-SUBSTITUTED BUTYRAMIDE DERIVATIVES CIBA-GEIGY AG (CH) 1986-01-03 WO claimed
EP-0063678-B1 PROCESS FOR THE PREPARATION OF CHOLESTEROL DERIVATIVES, AND INTERMEDIATE DERIVATIVES THEREFOR F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-08-21 EP claimed
US-4400295-A REACTION PRODUCT OF A FATTY ACID, AMINO ACID AND A SECONDARY COMPOUND LOIRE COSMETICS CO., LTD. (JP) 1983-08-23 US claimed
EP-0063678-A2 Process for the preparation of cholesterol derivatives, and intermediate derivatives therefor F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1982-11-03 EP claimed
US-4224319-A AMINO ACID, TRIGLYCERIDE, VITAMINS A AND E MARCADET ERNEST 1980-09-23 US claimed
US-4193983-A Labeled liposome particle compositions and immunoassays therewith SYVA COMPANY (US) 1980-03-18 US claimed
US-4093517-A FROM MICROORGANISMS IN A YEAST EXTRACT, FERMENTATION EASTMAN KODAK COMPANY (US) 1978-06-06 US claimed
US-4052263-A Production of cholesterol esterase using Nocardia cholesterolicum EASTMAN KODAK COMPANY (US) 1977-10-04 US claimed
US-4008127-A Process for the preparation of cholesterol oxidase BOEHRINGER MANNHEIM G.M.B.H. (DT) 1977-02-15 US claimed
US-3974188-A PHOSPHATE THE LION DENTIFRICE CO., LTD. (JA) 1976-08-10 US claimed