Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18498836 | 0.84 | FABP4 (0.45) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29798163 | 0.84 | FABP4 (0.45) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28395828 | 0.81 | FABP4 (0.41) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24110479 | 0.81 | HTR2C (0.41) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10274544 | 0.80 | NOTUM (0.59) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16835378 | 0.79 | KDM4E (0.50) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL20612446 | 0.79 | NOTUM (0.58) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23360817 | 0.79 | NOTUM (0.58) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11962998 | 0.79 | NOTUM (0.58) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30575088 | 0.79 | NOTUM (0.58) | NOTUMKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170924-B | Method for electrochemically synthesizing hexafluoroisopropoxyindole compound | 广西师范大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-111170924-A | Method for electrochemically synthesizing hexafluoroisopropoxy indole compound | 广西师范大学 | 2020-05-19 | — | — | CN | disclosed |