SCHEMBL28409183

SCHEMBL28409183

CCCCC(=O)NC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 2/20 0.67
ADORA2A P29274 1/20 0.58
ADORA2B P29275 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31307308 0.93 SLC29A1 (0.71) SLC29A1ADORA2AADORA2B
SCHEMBL31307319 0.90 SLC29A1 (0.73) SLC29A1ADORA2AADORA2B
SCHEMBL5195359 0.89 SLC29A1 (0.72) SLC29A1ADORA2AADORA2B
SCHEMBL20419163 0.89 SLC29A1 (0.72) SLC29A1ADORA2AADORA2B
SCHEMBL451885 0.87 ADORA2A (0.61) SLC29A1ADORA2AADORA2B
SCHEMBL29387907 0.87 ADORA2A (0.61) SLC29A1ADORA2AADORA2B
SCHEMBL451884 0.87 ADORA2A (0.61) SLC29A1ADORA2AADORA2B
SCHEMBL6474066 0.87 SLC29A1 (0.68) SLC29A1ADORA2AADORA2B
SCHEMBL6474053 0.87 SLC29A1 (0.68) SLC29A1ADORA2AADORA2B
SCHEMBL15158098 0.85 SLC29A1 (0.65) SLC29A1ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117377491-A Immunogenic compositions 葛兰素史克生物有限公司 2024-01-09 CN disclosed
CN-111246854-A Modified MRNA vaccines encoding herpes simplex virus glycoproteins and uses thereof 宾夕法尼亚大学理事会 2020-06-05 CN disclosed