SCHEMBL5195359

SCHEMBL5195359

CCCCCCC(=O)Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 2/20 0.72
TSHR P16473 2/20 0.60
PMP22 Q01453 1/20 0.60
ADORA3 P0DMS8 1/20 0.60
GAA P10253 1/20 0.60
ADORA2A P29274 1/20 0.60
ADORA2B P29275 1/20 0.60
ADORA1 P30542 1/20 0.60
HTT P42858 1/20 0.60
SIGMAR1 Q99720 1/20 0.60
RXFP1 Q9HBX9 1/20 0.60
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
TP53 P04637 1/20 0.60
NFKB1 P19838 1/20 0.60
HIF1A Q16665 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20419163 1.00 SLC29A1 (0.72) SLC29A1TSHRPMP22ADORA3GAA
SCHEMBL31307319 0.99 SLC29A1 (0.73) SLC29A1ADORA2AADORA2B
SCHEMBL31307308 0.96 SLC29A1 (0.71) SLC29A1ADORA2AADORA2B
SCHEMBL6474066 0.92 SLC29A1 (0.68) SLC29A1ADORA2AADORA2B
SCHEMBL6474053 0.92 SLC29A1 (0.68) SLC29A1ADORA2AADORA2B
SCHEMBL27570144 0.90 SLC29A1 (0.58) SLC29A1PMP22ADORA3GAAADORA2A
SCHEMBL27550539 0.90 SLC29A1 (0.58) SLC29A1PMP22ADORA3GAAADORA2A
SCHEMBL28409183 0.89 SLC29A1 (0.67) SLC29A1ADORA2AADORA2B
SCHEMBL31307310 0.88 SLC29A1 (0.67) SLC29A1ADORA2AADORA2B
SCHEMBL5193903 0.86 ADORA1 (0.62) ADORA3ADORA2AADORA2BADORA1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1554298-A4 PROCESS FOR THE PREPARATION OF 9-BETA-ANOMERIC NUCLEOSIDE ANALOGS ASH STEVENS INC (US) 2007-09-26 EP disclosed
EP-1554298-A1 PROCESS FOR THE PREPARATION OF 9-BETA-ANOMERIC NUCLEOSIDE ANALOGS ASH STEVENS, INC. (US) 2005-07-20 EP disclosed
US-6884880-B2 Process for the preparation of 9-β-anomeric nucleoside analogs ASH STEVENS, INC. (US) 2005-04-26 US disclosed
WO-2004018490-A1 PROCESS FOR THE PREPARATION OF 9-BETA-ANOMERIC NUCLEOSIDE ANALOGS ASH STEVENS, INC. (US) 2004-03-04 WO disclosed
US-20040039190-A1 Process for the preparation of 9-beta-anomeric nucleoside analogs ASH STEVENS, INC. 2004-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040039190-A1 Process for the preparation of 9-beta-anomeric nucleoside analogs DPYD, SLC29A2, GALE SLC29A1 4/4885TSHR 4066/4885PMP22 2423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.