SCHEMBL28409679

SCHEMBL28409679

NC(N)=NCCCC(N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.61
GLA P06280 1/20 0.61
TSHR P16473 1/20 0.61
NFKB1 P19838 1/20 0.61
APEX1 P27695 1/20 0.61
CYP2C19 P33261 1/20 0.61
NOS2 P35228 1/20 0.61
NPY1R P25929 3/20 0.59
NPY2R P49146 1/20 0.59
NPY4R P50391 1/20 0.59
C3AR1 Q16581 4/20 0.53
CHRM2 P08172 1/20 0.51
CHRM4 P08173 1/20 0.51
CHRM1 P11229 1/20 0.51
NPY5R Q15761 1/20 0.51
NRP1 O14786 3/20 0.49
EPHX2 P34913 1/20 0.49
CA2 P00918 1/20 0.49
SLC6A5 Q9Y345 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29356389 1.00 CYP1A2 (0.61) CYP1A2GLATSHRNFKB1APEX1
SCHEMBL30391184 1.00 CYP1A2 (0.61) CYP1A2GLATSHRNFKB1APEX1
SCHEMBL29603738 1.00 CYP1A2 (0.61) CYP1A2GLATSHRNFKB1APEX1
Hydrochloric Acid SCHEMBL1880117 0.97 CYP1A2 (0.58) CYP1A2GLATSHRNFKB1APEX1
SCHEMBL27898034 0.97 CYP2C19 (0.65) CYP1A2GLATSHRNFKB1APEX1
SCHEMBL1735525 0.97 CYP2C19 (0.65) CYP1A2GLATSHRNFKB1APEX1
Acetic Acid SCHEMBL29358131 0.96 NPY1R (0.59) CYP1A2GLATSHRNFKB1APEX1
SCHEMBL29351011 0.93 CYP1A2 (0.56) CYP1A2GLATSHRNFKB1APEX1
SCHEMBL1736266 0.92 NPY1R (0.55) CYP1A2GLATSHRNFKB1APEX1
SCHEMBL29566514 0.91 NPY1R (0.52) CYP1A2GLATSHRNFKB1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111297770-A Chinese herbal medicine anti-hair loss shampoo and preparation method thereof 戴金花 2020-06-19 CN disclosed