SCHEMBL1735525

SCHEMBL1735525

NC(N)=NCCC[C@H](NC(=O)[C@@H](N)CCCN=C(N)N)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.65
NOS2 P35228 2/20 0.65
CYP1A2 P05177 1/20 0.65
GLA P06280 1/20 0.65
TSHR P16473 1/20 0.65
NFKB1 P19838 1/20 0.65
APEX1 P27695 1/20 0.65
NPY1R P25929 1/20 0.55
NPY2R P49146 1/20 0.55
NPY4R P50391 1/20 0.55
C3AR1 Q16581 4/20 0.55
CHRM2 P08172 2/20 0.54
CHRM4 P08173 2/20 0.54
CHRM1 P11229 2/20 0.54
CA2 P00918 1/20 0.51
EPHX2 P34913 1/20 0.51
NRP1 O14786 4/20 0.51
SLC6A5 Q9Y345 1/20 0.50
MEN1 O00255 1/20 0.49
NOS3 P29474 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27898034 1.00 CYP2C19 (0.65) CYP2C19NOS2CYP1A2GLATSHR
SCHEMBL29603738 0.97 CYP1A2 (0.61) CYP2C19NOS2CYP1A2GLATSHR
SCHEMBL30391184 0.97 CYP1A2 (0.61) CYP2C19NOS2CYP1A2GLATSHR
SCHEMBL28409679 0.97 CYP1A2 (0.61) CYP2C19NOS2CYP1A2GLATSHR
SCHEMBL29356389 0.97 CYP1A2 (0.61) CYP2C19NOS2CYP1A2GLATSHR
Hydrochloric Acid SCHEMBL1880117 0.94 CYP1A2 (0.58) CYP2C19NOS2CYP1A2GLATSHR
SCHEMBL29351011 0.93 CYP1A2 (0.56) CYP2C19NOS2CYP1A2GLATSHR
SCHEMBL29353243 0.93 CYP1A2 (0.56) CYP2C19NOS2CYP1A2GLATSHR
Acetic Acid SCHEMBL29358131 0.93 NPY1R (0.59) CYP2C19NOS2CYP1A2GLATSHR
SCHEMBL31470824 0.93 CYP1A2 (0.56) CYP2C19NOS2CYP1A2GLATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 946 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107097-A1 SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF ENLAZA THERAPEUTICS, INC. (US) 2026-05-21 WO claimed
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN INC (US) 2026-05-07 US claimed
US-20260071252-A1 REVERSIBLE NANOPARTICLE AGGREGATES AND METHODS FOR DETECTING PROTEASES UNIV CALIFORNIA (US) 2026-03-12 US claimed
US-20260007756-A1 COMPOUND AND USE THEREOF COHERENT BIOPHARMA SUZHOU LTD (CN) 2026-01-08 US claimed
US-20260001910-A1 PEPTIDES AND USES THEREOF PREVECEUTICAL MEDICAL INC (CA) 2026-01-01 US claimed
EP-4663205-A1 POLYMER-DRUG CONJUGATE, INTERMEDIATE THEREOF, AND USE THEREOF Shanghai Best-Link Bioscience, LLC (CN) 2025-12-17 EP claimed
US-20250282838-A1 Multi-Epitope Vaccine for the Treatment of Alzheimer's Disease OTHAIR PROTHENA LIMITED (IE) 2025-09-11 US claimed
US-20250277002-A1 ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE PEPTILOGICS, INC. 2025-09-04 US claimed
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof IMMUNOGEN, INC. (US) 2025-08-19 US claimed
US-20250255977-A1 EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) 2025-08-14 US claimed
US-20220175761-A1 BI-LIGAND DRUG CONJUGATE AND USE THEREOF COHERENT BIOPHARMA SUZHOU LTD (CN) 2022-06-09 US claimed
US-11332535-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IMMUNOGEN, INC. (US) 2022-05-17 US claimed
CN-114450294-A Polypeptide with MMP2 inhibitory effect 大正制药株式会社 2022-05-06 CN claimed
US-20220135622-A1 ANTIBACTERIAL PEPTIDES AND METHODS OF USE GENENTECH, INC. (US) 2022-05-05 US claimed
US-20220111067-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN SWITZERLAND GMBH (CH) 2022-04-14 US claimed
WO-2022060488-A1 MULTIEPITOPE VACCINE FOR THE TREATMENT OF ALZHEIMER'S DISEASE OTHAIR PROTHENA LIMITED (IE) 2022-03-24 WO claimed
CN-114222756-A Biparatopic FR-alpha antibodies and immunoconjugates 伊缪诺金公司 2022-03-22 CN claimed
US-20220073898-A1 Tandem Protein Expression NOVOZYMES A/S (DK) 2022-03-10 US claimed
EP-3962935-A1 BIPARATOPIC FR-ALPHA ANTIBODIES AND IMMUNOCONJUGATES Immunogen, Inc. (US) 2022-03-09 EP claimed
EP-3941527-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES ImmunoGen, Inc. (US) 2022-01-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071252-A1 REVERSIBLE NANOPARTICLE AGGREGATES AND METHODS FOR DETECTING PROTEASES IDUA, XPNPEP1, CHIA CYP2C19 4777/4885NOS2 2488/4885CYP1A2 4770/4885
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof VIP, AREG, MIF CYP2C19 3914/4885NOS2 2151/4885CYP1A2 4637/4885
US-20220175761-A1 BI-LIGAND DRUG CONJUGATE AND USE THEREOF SLC10A1, CD47, SELPLG CYP2C19 1174/4885NOS2 4033/4885CYP1A2 2974/4885
US-20220111067-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VIP, AREG, MIF CYP2C19 3914/4885NOS2 2151/4885CYP1A2 4637/4885
US-20260001910-A1 PEPTIDES AND USES THEREOF MMP3, PEPD, MMP9 CYP2C19 2292/4885NOS2 1540/4885CYP1A2 2360/4885
US-20260007756-A1 COMPOUND AND USE THEREOF FOLH1, TRPV6, FOLR1 CYP2C19 1432/4885NOS2 1854/4885CYP1A2 2885/4885
US-20250255977-A1 EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF SLC7A1, KARS1, LNPEP CYP2C19 348/4885NOS2 1592/4885CYP1A2 1190/4885
US-20250277002-A1 ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE NGLY1, PRF1, LNPEP CYP2C19 4701/4885NOS2 2257/4885CYP1A2 4835/4885
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VEGFA, VIP, AREG CYP2C19 3681/4885NOS2 1504/4885CYP1A2 4565/4885
US-11332535-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IL23R, CD22, IL2RA CYP2C19 2796/4885NOS2 3621/4885CYP1A2 3278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.