Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 17/20 | 0.59 |
| ▸ | BRD9 | Q9H8M2 | 6/20 | 0.52 |
| ▸ | BRD4 | O60885 | 5/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.52 |
| ▸ | BRD1 | O95696 | 10/20 | 0.50 |
| ▸ | BRPF3 | Q9ULD4 | 6/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | BCL6 | P41182 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120017 | 0.87 | BRPF1 (0.50) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL16432414 | 0.83 | BRPF1 (0.52) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL1119967 | 0.81 | BRPF1 (0.45) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL31743117 | 0.80 | BRPF1 (0.57) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL31202712 | 0.78 | BRPF1 (0.62) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL28311122 | 0.78 | BRPF1 (0.56) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL11743970 | 0.76 | BRPF1 (0.76) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL26555542 | 0.76 | BRPF1 (0.68) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL7085783 | 0.74 | BRPF1 (1.00) | BRPF1BRD9BRD4CA12CA9 | |
| SCHEMBL1119899 | 0.73 | BRPF1 (0.59) | BRPF1BRD9BRD4CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116497-B | Preparation method of 3-methylquinoxaline-2- (1H) -one derivative | 温州医科大学 | 2021-05-25 | — | — | CN | disclosed |
| CN-111116497-A | Preparation method of 3-methylquinoxaline-2- (1H) -one derivative | 温州医科大学 | 2020-05-08 | — | — | CN | disclosed |