Coprostanol

Coprostanol

SCHEMBL28410

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OSBP P22059 1/20 0.78
OSBP2 Q969R2 1/20 0.78
CYP2C19 P33261 2/20 0.76
CYP2D6 P10635 1/20 0.76
ST6GAL1 P15907 2/20 0.75
INPP5D Q92835 1/20 0.74
GPBAR1 Q8TDU6 5/20 0.72
CASP7 P55210 3/20 0.72
HIF1A Q16665 3/20 0.72
TP53 P04637 2/20 0.72
MAPK1 P28482 2/20 0.72
HSD17B10 Q99714 2/20 0.72
BLM P54132 2/20 0.72
TDP1 Q9NUW8 2/20 0.72
VDR P11473 2/20 0.72
USP2 O75604 2/20 0.72
LMNA P02545 2/20 0.72
CYP3A4 P08684 2/20 0.72
MDM4 O15151 1/20 0.72
MAPT P10636 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Epicoprosterol SCHEMBL12607072 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL16867279 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL12453190 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL12806627 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL24632942 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL11380074 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL25267973 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL11391325 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL21000320 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL22018677 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3817 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139254-A1 INTERFERING RNA FOR INHIBITING TOP1 GENE EXPRESSION AND USE THEREOF JENKEM TECH CO LTD BEIJING (CN) 2026-05-21 US claimed
EP-4743437-A1 DIESTER LIPIDS, LIPID NANOPARTICLE CONTAINING DIESTER LIPIDS, AND FORMULATIONS THEREOF Providence Therapeutics Holdings Inc. (CA) 2026-05-20 EP claimed
EP-4737436-A1 CATIONIC LIPID CONTAINING TWO TERTIARY AMINE GROUPS, AND USE THEREOF Xiamen Sinopeg Biotech Co., Ltd (CN) 2026-05-06 EP claimed
WO-2026090505-A1 FLUOROPYRIMIDINE PARTICLES FOR THE TREATMENT OF CANCER WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2026-04-30 WO claimed
EP-4731258-A1 LIPID NANOPARTICLES CONTAINING DISULFIDE LIPIDS AND FORMULATIONS THEREOF Providence Therapeutics Holdings Inc. (CA) 2026-04-29 EP claimed
EP-4726038-A1 EXPRESSION-ADJUSTABLE ENGINEERED RNA MOLECULE Rinuagene Biotechnology Co., Ltd. (CN) 2026-04-15 EP claimed
EP-4721759-A1 LIPID NANOPARTICLE FOR DELIVERING NUCLEIC ACID DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF Cansino (Shanghai) Biological Research Co., Ltd. (CN) 2026-04-08 EP claimed
EP-4707289-A1 STEROID-CATIONIC LIPID COMPOUND AND USE THEREOF Cansino (Shanghai) Biological Research Co., Ltd. (CN) 2026-03-11 EP claimed
EP-4321504-B1 PEGYLATED LIPID AND LIPOSOME MODIFIED THEREBY, AND PHARMACEUTICAL COMPOSITION COMPRISING LIPOSOME AND PREPARATION AND USE THEREOF XIAMEN SINOPEG BIOTECH CO LTD (CN) 2026-02-18 EP claimed
EP-4342929-B1 POLYETHYLENE GLYCOL LIPID AND USE THEREOF JENKEM TECH CO LTD TIANJIN (CN) 2026-02-04 EP claimed
EP-0487674-B1 INJECTABLE SLOW-RELEASE GALENICAL APLICACIONES FARMACEUTICAS (MX) 1995-01-25 EP claimed
EP-0251905-B1 Esters of alginic acid FIDIA SPA (IT) 1994-11-02 EP claimed
EP-0609968-A2 Compositions comprising partial esters of alginic acid FIDIA S.p.A. (IT) 1994-08-10 EP claimed
WO-1993004672-A1 METHOD FOR ENHANCING THE IMMUNE SYSTEM IN A HOST EMPLOYING LIPOSOME-ENCAPSULATED POLYPEPTIDES PITMAN-MOORE, INC. (US) 1993-03-18 WO claimed
EP-0246540-B1 IMPLANT PREPARATIONS FOR DELIVERY OF BIOACTIVE MACROMOLECULES Wang, Paul Y. (CA) 1992-08-05 EP claimed
US-5110595-A Compression of mixture of polypeptide and lipid powder WANG PAUL Y (CA) 1992-05-05 US claimed
US-4921710-A Method of converting cholesterol in food to coprostanol IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 1990-05-01 US claimed
CN-87104499-A Novel alginic acid esters 1988-04-06 CN claimed
EP-0251905-A2 Esters of alginic acid FIDIA S.p.A. (IT) 1988-01-07 EP claimed
EP-0246540-A2 Implant preparations for delivery of bioactive macromolecules Wang, Paul Y. (CA) 1987-11-25 EP claimed