Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28413114 | 0.83 | KDR (0.46) | PDE3BPDE3APDE10AKDRCA1 | |
| SCHEMBL29056086 | 0.80 | NPC1 (0.45) | KDRCA1CA2CA9CA12 | |
| SCHEMBL29250116 | 0.80 | TP53 (0.46) | PDE3BPDE3APDE10AALDH1A1CYP2D6 | |
| SCHEMBL31556358 | 0.79 | PDE3B (0.47) | PDE3BPDE3APDE10AKDRCA1 | |
| Ammonia Solution, Strong SCHEMBL29153964 | 0.79 | PDE3B (0.58) | PDE3BPDE3APDE10AKDRCA1 | |
| SCHEMBL29999550 | 0.76 | ALDH1A1 (0.54) | PDE3BPDE3APDE10APOLBALDH1A1 | |
| SCHEMBL26131691 | 0.76 | ALDH1A1 (0.54) | PDE3BPDE3APDE10APOLBALDH1A1 | |
| SCHEMBL20609814 | 0.76 | NPSR1 (0.48) | PDE3BPDE3APDE10AKDRCA1 | |
| SCHEMBL29162293 | 0.75 | KDR (0.49) | PDE3BPDE3APDE10AKDRCA1 | |
| SCHEMBL28383956 | 0.72 | ALDH1A1 (0.46) | KDRCA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132974-B | Sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-111132974-A | Novel sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-110914256-A | Novel sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2020-03-24 | — | — | CN | disclosed |