Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 9/20 | 0.65 |
| ▸ | SKP2 | Q13309 | 9/20 | 0.65 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.61 |
| ▸ | TOP2A | P11388 | 5/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophene SCHEMBL28413445 | 0.90 | CKS1B (0.61) | CKS1BSKP2GLO1TOP2AATM | |
| SCHEMBL28160383 | 0.83 | CKS1B (0.60) | CKS1BSKP2GLO1TOP2AKMT2A | |
| SCHEMBL21869669 | 0.81 | CKS1B (0.68) | CKS1BSKP2GLO1TOP2A | |
| SCHEMBL17506542 | 0.80 | CKS1B (1.00) | CKS1BSKP2GLO1 | |
| SCHEMBL28160390 | 0.80 | CKS1B (0.55) | CKS1BSKP2GLO1TOP2AMEN1 | |
| SCHEMBL28847330 | 0.78 | CKS1B (0.56) | CKS1BSKP2GLO1TOP2A | |
| SCHEMBL28160394 | 0.77 | SOAT1 (0.61) | CKS1BSKP2GLO1 | |
| SCHEMBL21869715 | 0.76 | CKS1B (0.64) | CKS1BSKP2GLO1 | |
| SCHEMBL23360233 | 0.76 | KMT2A (0.64) | CKS1BSKP2ATMMEN1KMT2A | |
| SCHEMBL29862447 | 0.76 | KMT2A (0.64) | CKS1BSKP2ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106938984-B | 5-substituted arylation/heterocycle 8-acylamino quinoline compound and one-pot preparation method thereof | 湖南大学 | 2020-05-05 | — | — | CN | disclosed |