Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.53 |
| ▸ | CKS1B | P61024 | 3/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29862447 | 1.00 | KMT2A (0.64) | KMT2ATP53RXFP1MEN1ATM | |
| SCHEMBL28424813 | 0.84 | KMT2A (0.60) | KMT2ATP53RXFP1MEN1SLC40A1 | |
| SCHEMBL9367514 | 0.82 | KMT2A (0.57) | KMT2ATP53RXFP1MEN1SLC40A1 | |
| SCHEMBL28419837 | 0.82 | ATM (0.54) | KMT2ATP53RXFP1MEN1ATM | |
| SCHEMBL17597171 | 0.82 | KDM4E (0.57) | KMT2AMEN1ATMSLC40A1ALDH1A1 | |
| SCHEMBL29862819 | 0.81 | KMT2A (0.74) | KMT2ATP53MEN1SLC40A1CKS1B | |
| SCHEMBL23360257 | 0.81 | KMT2A (0.74) | KMT2ATP53MEN1SLC40A1CKS1B | |
| SCHEMBL11638651 | 0.79 | ATM (0.52) | KMT2ATP53RXFP1MEN1ATM | |
| SCHEMBL6785564 | 0.79 | KMT2A (0.56) | KMT2ATP53MEN1SLC40A1CKS1B | |
| SCHEMBL10889120 | 0.78 | COMT (0.58) | KMT2AMEN1ATMSLC40A1CKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055014-B1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORP (KR) | 2025-04-30 | — | — | EP | disclosed |
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| US-11655235-B2 | Pyrrolidine and piperidine compounds | YUHAN CORPORATION (KR) | 2023-05-23 | — | — | US | disclosed |
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |
| CN-111320579-B | Preparation method of 8-amide-5-halogenated quinoline derivative | 常州工程职业技术学院 | 2021-06-29 | — | — | CN | disclosed |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORPORATION (KR) | 2021-05-20 | — | — | US | disclosed |
| CN-111320579-A | Preparation method of 8-amide-5-halogenated quinoline derivative | 常州工程职业技术学院 | 2020-06-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | FAP, APC, VHL | KMT2A 2822/4885TP53 102/4885RXFP1 3178/4885 |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | FAP, APC, VHL | KMT2A 2822/4885TP53 102/4885RXFP1 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.