SCHEMBL28411968

SCHEMBL28411968

CC(O)C(NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSK P43235 8/20 0.47
CTSS P25774 3/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CYP2D6 P10635 1/20 0.46
PREP P48147 1/20 0.41
CTSL P07711 2/20 0.40
CTSB P07858 2/20 0.40
TRPA1 O75762 1/20 0.40
CA12 O43570 1/20 0.40
CA14 Q9ULX7 1/20 0.40
SRC P12931 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20825614 1.00 CTSK (0.47) CTSKCTSSCA1CA2CA7
SCHEMBL10280834 1.00 CTSK (0.47) CTSKCTSSCA1CA2CA7
SCHEMBL2772892 1.00 CTSK (0.47) CTSKCTSSCA1CA2CA7
SCHEMBL5886446 0.91 CTSK (0.46) CTSKCTSSCA1CA2CA7
SCHEMBL5886445 0.91 CTSK (0.46) CTSKCTSSCA1CA2CA7
SCHEMBL1486173 0.91 CTSK (0.46) CTSKCTSSCA1CA2CA7
SCHEMBL1486171 0.91 CTSK (0.46) CTSKCTSSCA1CA2CA7
SCHEMBL22527163 0.91 CTSK (0.46) CTSKCTSSCA1CA2CA7
SCHEMBL8048104 0.91 CTSK (0.46) CTSKCTSSCA1CA2CA7
SCHEMBL5343118 0.91 CTSK (0.46) CTSKCTSSCA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304131-A Alpha-carbonyl alkenyl ester compound, and preparation method and application thereof 广州医科大学 2023-12-29 CN disclosed
CN-111148739-A Cyclopeptide antibiotics 豪夫迈·罗氏有限公司 2020-05-12 CN disclosed