SCHEMBL28413161

SCHEMBL28413161

CSc1nc(N(O)C(=O)[C@@H](N)C(C)C)c2ncn(C(N)=O)c2n1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 1/20 0.32
▸ ADORA1 P30542 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28418221 0.81 GSK3B (0.35) ADORA2AADORA1
Threonine SCHEMBL28963051 0.76 P2RY1 (0.36) ADORA2AADORA1
SCHEMBL29238707 0.75 KDM4E (0.52) ADORA2A
SCHEMBL29238705 0.75 KDM4E (0.52) ADORA2A
SCHEMBL31192291 0.74 HTR2C (0.31) —
SCHEMBL28521252 0.74 HTR2C (0.31) —
SCHEMBL26603870 0.72 ADORA2A (0.34) ADORA2AADORA1
SCHEMBL28413163 0.67 — —
SCHEMBL29002283 0.65 CYP1A2 (0.36) ADORA2AADORA1
SCHEMBL31360412 0.57 CYP1A2 (0.37) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751285-A Lipid compounds and lipid nanoparticle compositions 中生复诺健生物科技(上海)有限公司 2025-04-04 — — CN disclosed
CN-116829578-B Polynucleotides encoding interleukin-12 (IL-12) and compositions and methods related thereto 苏州艾博生物科技有限公司 2025-03-21 — — CN disclosed
CN-119654141-A Lipid nanoparticle compositions 苏州艾博生物科技有限公司 2025-03-18 — — CN disclosed
CN-117083291-B Coronavirus nucleic acid vaccine based on sequences derived from SARS-CoV-2 Delta strain 苏州艾博生物科技有限公司 2025-02-28 — — CN disclosed
CN-119451976-A Mutant fragments of VZV glycoprotein E 苏州艾博生物科技有限公司 2025-02-14 — — CN disclosed
CN-119137160-A Nucleic acid vaccine for Respiratory Syncytial Virus (RSV) 苏州艾博生物科技有限公司 2024-12-13 — — CN disclosed
CN-117580587-B Coronavirus nucleic acid vaccine based on sequences derived from SARS-CoV-2 Omikovia strain 苏州艾博生物科技有限公司 2024-10-15 — — CN disclosed
CN-118715201-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2024-09-27 — — CN disclosed
CN-118647397-A Polynucleotide composition and use thereof 辉瑞公司 2024-09-13 — — CN disclosed
CN-114206463-B Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2024-06-11 — — CN disclosed
CN-116829578-A Polynucleotides encoding interleukin-12 (IL-12) and compositions and methods related thereto 苏州艾博生物科技有限公司 2023-09-29 — — CN disclosed
CN-116670267-A Tetravalent mRNA vaccine for influenza virus 苏州艾博生物科技有限公司 2023-08-29 — — CN disclosed
CN-116472275-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-07-21 — — CN disclosed
CN-116323627-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-06-23 — — CN disclosed
CN-114206827-B Lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-05-23 — — CN disclosed
CN-114391008-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2022-04-22 — — CN disclosed
CN-114206463-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2022-03-18 — — CN disclosed
CN-114206827-A Lipid nanoparticle compositions 苏州艾博生物科技有限公司 2022-03-18 — — CN disclosed
CN-113271926-A Preparation of lipid nanoparticles and methods of administration thereof 摩登纳特斯有限公司 2021-08-17 — — CN disclosed
CN-111315359-A Method for preparing lipid nanoparticles 摩登纳特斯有限公司 2020-06-19 — — CN disclosed
Send feedback