SCHEMBL26603870

SCHEMBL26603870

CSc1nc(NC(=O)[C@@H](N)[C@@H](C)O)c2ncn(C(N)=O)c2n1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 1/20 0.34
▸ ADORA1 P30542 1/20 0.34
▸ HTR2B P41595 2/20 0.32
▸ HTR2C P28335 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ SPHK1 Q9NYA1 4/20 0.30
▸ ADORA3 P0DMS8 1/20 0.30
▸ ADRA2B P18089 1/20 0.30
▸ HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29116493 0.80 GSK3B (0.36) ADORA2AADORA1SPHK1ADORA3
Threonine SCHEMBL28963051 0.79 P2RY1 (0.36) ADORA2AADORA1KMT2A
SCHEMBL29278769 0.74 SPHK1 (0.32) MEN1KMT2ASPHK1
SCHEMBL26090156 0.74 HTR2B (0.35) ADORA1HTR2BHTR2CADORA3ADRA2B
SCHEMBL29413061 0.74 HTR2B (0.35) ADORA1HTR2BHTR2CADORA3ADRA2B
SCHEMBL28894183 0.74 ADORA3 (0.54) ADORA1ADORA3
SCHEMBL28894185 0.74 ADORA3 (0.54) ADORA1ADORA3
SCHEMBL574739 0.73 P2RY1 (0.50) KMT2A
SCHEMBL28413161 0.72 ADORA2A (0.32) ADORA2AADORA1
SCHEMBL29238711 0.72 HTR2B (0.34) HTR2BHTR2CADORA3ADRA2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023141474-A9 POLY-TAILED AND POLY-CAPPED MRNA AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2023-10-26 — — WO claimed
CN-119751285-A Lipid compounds and lipid nanoparticle compositions 中生复诺健生物科技(上海)有限公司 2025-04-04 — — CN disclosed
CN-116829578-B Polynucleotides encoding interleukin-12 (IL-12) and compositions and methods related thereto 苏州艾博生物科技有限公司 2025-03-21 — — CN disclosed
CN-119654141-A Lipid nanoparticle compositions 苏州艾博生物科技有限公司 2025-03-18 — — CN disclosed
CN-117083291-B Coronavirus nucleic acid vaccine based on sequences derived from SARS-CoV-2 Delta strain 苏州艾博生物科技有限公司 2025-02-28 — — CN disclosed
CN-119451976-A Mutant fragments of VZV glycoprotein E 苏州艾博生物科技有限公司 2025-02-14 — — CN disclosed
CN-119137160-A Nucleic acid vaccine for Respiratory Syncytial Virus (RSV) 苏州艾博生物科技有限公司 2024-12-13 — — CN disclosed
CN-117580587-B Coronavirus nucleic acid vaccine based on sequences derived from SARS-CoV-2 Omikovia strain 苏州艾博生物科技有限公司 2024-10-15 — — CN disclosed
CN-118715201-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2024-09-27 — — CN disclosed
CN-118697900-A Method for preparing lipid nanoparticles 摩登纳特斯有限公司 2024-09-27 — — CN disclosed
CN-117043343-A Nucleic acid vaccine for mutant coronaviruses 苏州艾博生物科技有限公司 2023-11-10 — — CN disclosed
CN-117003658-A Lipid Nanoparticle Compositions 苏州艾博生物科技有限公司 2023-11-07 — — CN disclosed
CN-116940685-A Coronavirus multivalent nucleic acid vaccine based on sequences derived from SARS-CoV-2Beta and Delta strains 苏州艾博生物科技有限公司 2023-10-24 — — CN disclosed
CN-116829578-A Polynucleotides encoding interleukin-12 (IL-12) and compositions and methods related thereto 苏州艾博生物科技有限公司 2023-09-29 — — CN disclosed
CN-116782889-A Enhanced formulation stability and improved lyophilization process 生物技术欧洲股份公司 2023-09-19 — — CN disclosed
CN-116670267-A Tetravalent mRNA vaccine for influenza virus 苏州艾博生物科技有限公司 2023-08-29 — — CN disclosed
CN-116472275-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-07-21 — — CN disclosed
CN-116323627-A Lipid compounds and lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-06-23 — — CN disclosed
CN-114206827-B Lipid nanoparticle compositions 苏州艾博生物科技有限公司 2023-05-23 — — CN disclosed
CN-110520409-A Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX INC 2019-11-29 — — CN disclosed
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