Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL2906117 | 0.83 | DNM1 (0.46) | TLR8ALDH1A1MEN1KMT2A | |
| Anthracene SCHEMBL11035788 | 0.79 | MEN1 (0.47) | TLR8ALDH1A1MEN1NPC1KMT2A | |
| Quinazoline SCHEMBL8654846 | 0.77 | EGFR (0.65) | TLR8 | |
| Naphthalene SCHEMBL5965913 | 0.76 | DNM1 (0.57) | TLR8ALDH1A1MEN1KMT2A | |
| Biphenyl SCHEMBL9641413 | 0.76 | TAAR1 (0.46) | TLR8ALDH1A1MEN1KMT2A | |
| Aniline SCHEMBL11819261 | 0.74 | TSHR (0.52) | TLR8ALDH1A1MEN1KMT2A | |
| Naphthalene SCHEMBL11586730 | 0.74 | DNM1 (0.62) | TLR8ALDH1A1MEN1KMT2A | |
| Toluene SCHEMBL21981119 | 0.74 | TSHR (0.52) | TLR8ALDH1A1MEN1KMT2A | |
| Naphthalene SCHEMBL16466617 | 0.74 | DNM1 (0.62) | TLR8ALDH1A1MEN1KMT2A | |
| Toluene SCHEMBL1989071 | 0.74 | TSHR (0.52) | TLR8ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303057-B | Phenazine derivative with nitrogen-containing side chain and preparation method and application thereof | 南通大学 | 2022-01-25 | — | — | CN | disclosed |
| CN-111303057-A | Phenazine derivative with nitrogen-containing side chain and preparation method and application thereof | 南通大学 | 2020-06-19 | — | — | CN | disclosed |