SCHEMBL284142

SCHEMBL284142

NC(=O)c1cccc(F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 7/20 1.00
CES2 O00748 2/20 0.68
CES1 P23141 2/20 0.68
HDAC1 Q13547 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
CYP1A2 P05177 1/20 0.55
PKM P14618 1/20 0.54
HPGDS O60760 1/20 0.53
TSHR P16473 2/20 0.52
POLB P06746 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
CYP2C19 P33261 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
PMP22 Q01453 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
KCNN4 O15554 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30151881 1.00 PARP1 (1.00) PARP1CES2CES1HDAC1HDAC6
SCHEMBL18867942 1.00 PARP1 (1.00) PARP1CES2CES1HDAC1HDAC6
Hydrochloric Acid SCHEMBL28788495 0.98 PARP1 (0.96) PARP1CES2CES1HDAC1HDAC6
Hydrochloric Acid SCHEMBL30460793 0.98 PARP1 (0.96) PARP1CES2CES1HDAC1HDAC6
Hydrochloric Acid SCHEMBL4381068 0.98 PARP1 (0.96) PARP1CES2CES1HDAC1HDAC6
Formic Acid SCHEMBL31754222 0.92 PARP1 (0.85) PARP1CES2CES1HDAC1HDAC6
Phosphoric Acid SCHEMBL27813451 0.92 PARP1 (0.85) PARP1CES2CES1HDAC1HDAC6
3-Aminobenzamide SCHEMBL27579659 0.90 PARP1 (0.81) PARP1CES2CES1HDAC1HDAC6
Benzoic Acid SCHEMBL28349303 0.90 PARP1 (0.81) PARP1CES2CES1HDAC1HDAC6
SCHEMBL27675361 0.89 PARP1 (0.79) PARP1CES2CES1HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070277-A Androgen receptor PROTAC 葛兰素史密斯克莱知识产权发展有限公司 2026-05-19 CN claimed
EP-4121421-B1 BIARYL DERIVATIVES AS YAP/TAZ-TEAD PROTEIN-PROTEIN INTERACTION INHIBITORS NOVARTIS AG (CH) 2026-03-11 EP claimed
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP claimed
EP-4651717-A1 COMPOUNDS FOR INCREASING FROST TOLERANCE IN PLANTS VIB VZW (BE) 2025-11-26 EP claimed
US-12410174-B1 Small molecular inhibitors of sting signaling compositions and methods of use TYERELL IMMUNOTHERAPEUTICS INC (US) 2025-09-09 US claimed
CN-120049017-A Org/ZnSO4Electrolyte, preparation method thereof and application of electrolyte in secondary battery 同济大学 2025-05-27 CN claimed
CN-120004697-A Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material 同济大学 2025-05-16 CN claimed
CN-115298170-B Biaryl derivatives as YAP/TAZ-TEAD protein-protein interaction inhibitors 诺华股份有限公司 2024-09-27 CN claimed
CN-118696036-A PARP1 inhibitors 突触活化疗法股份有限公司 2024-09-24 CN claimed
CN-118507836-B Electrolyte for secondary lithium metal battery 深圳欣界能源科技有限公司 2024-09-17 CN claimed
WO-1999032477-A1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AKTIENGESELLSCHAFT (DE) 1999-07-01 WO claimed
WO-1999031491-A1 METHOD AND REAGENTS FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-06-24 WO claimed
US-5874444-A CONTROLLING CELL AGING GERON CORPORATION (US) 1999-02-23 US claimed
EP-0696270-B1 4-AMINO-FLUOROBENZAMIDES AND THEIR USE AS CYTOTOXIC PRODRUGS CANCER RES CAMPAIGN TECH (GB) 1998-11-04 EP claimed
US-5811454-A 3-FLUOROBENZAMIDES WITH NITROGEN MUSTARD GROUPS; ANTICARCINOGENIC AGENTS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1998-09-22 US claimed
WO-1998027975-A1 POLY(ADP-RIBOSE) POLYMERASE INHIBITORS TO TREAT DISEASES ASSOCIATED WITH CELLULAR SENESCENCE GERON CORPORATION (US) 1998-07-02 WO claimed
JP-H08509490-A 1996-10-08 JP claimed
EP-0696270-A1 4-AMINO-FLUOROBENZAMIDES AND THEIR USE AS CYTOTOXIC PRODRUGS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1996-02-14 EP claimed
WO-1994025429-A1 4-AMINO-FLUOROBENZAMIDES AND THEIR USE AS CYTOTOXIC PRODRUGS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1994-11-10 WO claimed
WO-1993014062-A1 ANTHELMINTIC β-KETOAMIDES THE UPJOHN COMPANY (US) 1993-07-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12410174-B1 Small molecular inhibitors of sting signaling compositions and methods of use STING1, IRF3, MAVS PARP1 246/4885CES2 4707/4885CES1 4324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.