Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.76 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28408663 | 0.91 | HDAC6 (0.75) | HDAC6DRD3HTR1AHTR2A | |
| SCHEMBL2228828 | 0.86 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL28413850 | 0.85 | HDAC6 (0.73) | HDAC6 | |
| SCHEMBL30309434 | 0.79 | HDAC6 (0.49) | HDAC6DRD3HTR1AHTR2A | |
| SCHEMBL2225175 | 0.76 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL28410590 | 0.76 | HDAC6 (0.72) | HDAC6 | |
| SCHEMBL1364346 | 0.75 | HDAC1 (0.76) | HDAC6 | |
| SCHEMBL1364426 | 0.75 | HDAC1 (0.76) | HDAC6 | |
| SCHEMBL28408662 | 0.75 | HDAC6 (0.74) | HDAC6 | |
| SCHEMBL2225339 | 0.74 | HDAC6 (1.00) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110885316-B | Sulfhydryl compound as histone deacetylase inhibitor and application thereof | 上海中泽医药科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-110885316-A | Sulfhydryl compound as histone deacetylase inhibitor and application thereof | 上海中泽医药科技有限公司 | 2020-03-17 | — | — | CN | disclosed |