SCHEMBL28414628

SCHEMBL28414628

Nc1ccc(Oc2ccc(-c3ccccn3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
APAF1 O14727 1/20 0.56
CYP1A2 P05177 2/20 0.54
CYP2D6 P10635 1/20 0.54
CYP19A1 P11511 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
MAOA P21397 2/20 0.53
ALDH1A1 P00352 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
BTK Q06187 1/20 0.46
MAPT P10636 3/20 0.46
MITF O75030 1/20 0.46
GAA P10253 1/20 0.46
GFER P55789 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71031 0.89 KDM4E (0.56) MEN1KMT2ACYP1A2CYP2D6CYP19A1
SCHEMBL2194874 0.87 CYP1A2 (0.59) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL18555517 0.87 KDM4E (0.54) MEN1KMT2ACYP1A2CYP2D6CYP19A1
Hydrochloric Acid SCHEMBL29687884 0.87 KDM4E (0.54) MEN1KMT2ACYP1A2CYP2D6CYP19A1
SCHEMBL18745786 0.87 KDM4E (0.54) MEN1KMT2ACYP1A2CYP2D6CYP19A1
Hydrochloric Acid SCHEMBL7130341 0.87 KDM4E (0.54) MEN1KMT2ACYP1A2CYP2D6CYP19A1
Hydrochloric Acid SCHEMBL7130326 0.85 KDM4E (0.52) MEN1KMT2ACYP1A2CYP2D6CYP19A1
SCHEMBL22529961 0.84 KDM4E (0.56) MEN1KMT2AAPAF1CYP1A2CYP2D6
SCHEMBL29353245 0.84 KDM4E (0.56) MEN1KMT2AAPAF1CYP1A2CYP2D6
SCHEMBL21882472 0.83 CYP1A2 (0.51) MEN1KMT2ACYP1A2CYP2D6CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117999165-A Heat-resistant laminate 蓝移材料有限公司 2024-05-07 CN disclosed
CN-111433265-B Heat treated polyamide-amide aerogel 蓝移材料有限公司 2023-09-29 CN disclosed
CN-115734868-A High temperature resistant thermal insulating laminate comprising aerogel layer 蓝移材料有限公司 2023-03-03 CN disclosed
CN-115734871-A Low dielectric constant, low dissipation factor laminate comprising aerogel layer 蓝移材料有限公司 2023-03-03 CN disclosed
CN-110944744-B Macroporous polymeric aerogels 蓝移材料有限公司 2023-01-31 CN disclosed
CN-108699277-B Polymeric aerogels with improved mechanical and thermal properties 蓝移材料有限公司 2022-12-02 CN disclosed
CN-110461926-B Organic polymeric aerogels containing microstructures 蓝移材料有限公司 2022-06-28 CN disclosed
CN-108348871-B Highly branched, non-crosslinked aerogels, method for the production thereof and use thereof 蓝移材料有限公司 2021-11-05 CN disclosed
CN-112313004-A Polymer aerogels prepared by solvent-free exchange 蓝移材料有限公司 2021-02-02 CN disclosed
CN-111433265-A Heat-treated polyamide amide aerogels 蓝移材料有限公司 2020-07-17 CN disclosed
CN-110944744-A Macroporous polymeric aerogels 蓝移材料有限公司 2020-03-31 CN disclosed