Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CCR1 | P32246 | 2/20 | 0.54 |
| ▸ | CCR5 | P51681 | 2/20 | 0.54 |
| ▸ | CCR8 | P51685 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7130326 | 0.98 | KDM4E (0.52) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL71031 | 0.98 | KDM4E (0.56) | KDM4ELMNACYP1A2CCR1CCR5 | |
| Hydrochloric Acid SCHEMBL7130341 | 0.96 | KDM4E (0.54) | KDM4ELMNACYP1A2CCR1CCR5 | |
| Hydrochloric Acid SCHEMBL18555517 | 0.96 | KDM4E (0.54) | KDM4ELMNACYP1A2CCR1CCR5 | |
| Hydrochloric Acid SCHEMBL29687884 | 0.96 | KDM4E (0.54) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL29984274 | 0.89 | KDM4E (0.68) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL13458076 | 0.89 | KDM4E (0.68) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL18745762 | 0.88 | CYP2A6 (0.52) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL28414628 | 0.87 | MEN1 (0.56) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL18745704 | 0.87 | ASIC3 (0.55) | KDM4ELMNACYP1A2CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624193-B2 | Cyclic azine derivatives, processes for producing these, and organic electroluminescent element containing these as component | TOSOH CORPORATION (JP) | 2017-04-18 | — | — | US | disclosed |