SCHEMBL28414751

SCHEMBL28414751

O=CNNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
MAPT P10636 6/20 0.51
MAPK1 P28482 5/20 0.51
TDP1 Q9NUW8 4/20 0.49
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
ALDH1A1 P00352 5/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
TP53 P04637 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
GPR35 Q9HC97 1/20 0.47
HIF1A Q16665 1/20 0.47
TXNRD1 Q16881 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11295740 0.83 MEN1 (0.54) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL8861422 0.82 HSD17B10 (0.53) LMNAMEN1KMT2AMAPTMAPK1
SCHEMBL9204359 0.82 CXCR2 (0.50) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL4631056 0.79 MAPT (0.54) LMNAMEN1KMT2AMAPTMAPK1
SCHEMBL10519866 0.79 MEN1 (0.54) LMNAMEN1KMT2AMAPTMAPK1
SCHEMBL11683270 0.78 HTT (0.59) LMNAKMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL31715811 0.78 MAPT (0.73) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL10551420 0.77 ALDH1A1 (0.53) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL28251934 0.77 MEN1 (0.63) LMNAMEN1KMT2AMAPTMAPK1
SCHEMBL28247113 0.77 MAPT (0.51) LMNAMEN1KMT2AMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113376296-B Method for measuring free formaldehyde content in curing agent 浙江万盛股份有限公司 2023-04-28 CN disclosed
CN-113376296-A Method for measuring content of free formaldehyde in curing agent 浙江万盛股份有限公司 2021-09-10 CN disclosed
CN-111289418-A Mask detection method 上海育仪科技有限公司 2020-06-16 CN disclosed