Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28415459 | 0.98 | NAAA (0.34) | NAAAEPHX1EPHX2 | |
| Formic Acid SCHEMBL28421232 | 0.94 | CYP1A2 (0.33) | NAAAEPHX1EPHX2CETP | |
| SCHEMBL10337151 | 0.90 | CYP1A2 (0.38) | NAAAEPHX1EPHX2BACE1BACE2 | |
| SCHEMBL27616200 | 0.90 | CYP1A2 (0.38) | NAAAEPHX1EPHX2BACE1BACE2 | |
| SCHEMBL2748993 | 0.90 | CYP1A2 (0.38) | NAAAEPHX1EPHX2BACE1BACE2 | |
| SCHEMBL8861201 | 0.90 | CYP1A2 (0.38) | NAAAEPHX1EPHX2BACE1BACE2 | |
| SCHEMBL7738990 | 0.90 | CYP1A2 (0.38) | NAAAEPHX1EPHX2BACE1BACE2 | |
| SCHEMBL10337191 | 0.90 | CYP1A2 (0.38) | NAAAEPHX1EPHX2BACE1BACE2 | |
| Formic Acid SCHEMBL28417895 | 0.89 | CYP3A4 (0.35) | — | |
| SCHEMBL8861264 | 0.88 | CYP1A2 (0.39) | NAAAEPHX1EPHX2BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336814-B | 4- (alkyl dicyclohexyl) -substituted naphthalimide derivative, and preparation method and application thereof | 大连理工大学 | 2020-08-14 | — | — | CN | claimed |
| CN-109180639-B | Substituted naphthalimide derivative, preparation method and application thereof | 大连理工大学 | 2020-06-02 | — | — | CN | claimed |
| CN-109336814-B | 4- (alkyl dicyclohexyl) -substituted naphthalimide derivative, and preparation method and application thereof | 大连理工大学 | 2020-08-14 | — | — | CN | disclosed |
| CN-109180639-B | Substituted naphthalimide derivative, preparation method and application thereof | 大连理工大学 | 2020-06-02 | — | — | CN | disclosed |