Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 4/20 | 0.52 |
| ▸ | EGFR | P00533 | 16/20 | 0.51 |
| ▸ | BTK | Q06187 | 2/20 | 0.48 |
| ▸ | PLK4 | O00444 | 1/20 | 0.48 |
| ▸ | GAK | O14976 | 1/20 | 0.48 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | BLK | P51451 | 1/20 | 0.48 |
| ▸ | BMX | P51813 | 1/20 | 0.48 |
| ▸ | CTSC | P53634 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | ITK | Q08881 | 1/20 | 0.48 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.48 |
| ▸ | DCLK3 | Q9C098 | 1/20 | 0.48 |
| ▸ | NUAK2 | Q9H093 | 1/20 | 0.48 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.48 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28384151 | 0.93 | ALK (0.47) | JAK3EGFRALK | |
| SCHEMBL16515023 | 0.91 | JAK3 (0.61) | JAK3EGFRBTKPLK4GAK | |
| SCHEMBL28416821 | 0.89 | FGFR1 (0.63) | JAK3EGFRBTKPLK4GAK | |
| SCHEMBL28417562 | 0.86 | EGFR (0.53) | JAK3EGFRBTKJAK2FLT3 | |
| SCHEMBL29847768 | 0.86 | EGFR (0.68) | EGFRBTKFGFR1KDR | |
| SCHEMBL16515005 | 0.86 | EGFR (0.68) | EGFRBTKFGFR1KDR | |
| SCHEMBL28383519 | 0.85 | — | — | |
| SCHEMBL28383234 | 0.85 | FGFR1 (0.49) | FGFR1KDR | |
| SCHEMBL28887740 | 0.85 | FGFR1 (0.53) | JAK3EGFRALKFGFR1KDR | |
| SCHEMBL16513541 | 0.84 | EGFR (0.60) | JAK3EGFRBTKPLK4GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285813-A | Chemical entities, compositions, and methods | 润新生物公司 | 2020-06-16 | — | — | CN | disclosed |