Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | CKS1B | P61024 | 1/20 | 0.49 |
| ▸ | SKP1 | P63208 | 1/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1393764 | 0.99 | MAPT (0.56) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL29426702 | 0.99 | MAPT (0.56) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL26641577 | 0.97 | MAPT (0.58) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL29437363 | 0.97 | GPR119 (0.55) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL30316131 | 0.94 | CKS1B (0.53) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL1990159 | 0.94 | CKS1B (0.53) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL26641386 | 0.92 | GPR119 (0.52) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL30643550 | 0.92 | GPR119 (0.52) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL28767159 | 0.89 | MAP4K4 (0.51) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL23783349 | 0.88 | GPR119 (0.67) | GPR119MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108283644-B | Transient protection of normal cells during chemotherapy | G1治疗公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-108434149-B | HSPC-sparing therapy for Rb-positive abnormal cell proliferation | G1治疗公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-107417691-B | Highly effective anti-neoplastic and anti-proliferative agents | G1治疗公司 | 2020-06-26 | — | — | CN | disclosed |