Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.71 |
| ▸ | SELP | P16109 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860525 | 0.94 | SELL (0.79) | SELLSELPCYP1A2LDHAALDH1A1 | |
| SCHEMBL176255 | 0.94 | SELL (0.79) | SELLSELPCYP1A2LDHAALDH1A1 | |
| SCHEMBL29030098 | 0.91 | SELL (0.75) | SELLSELPCYP1A2LDHAALDH1A1 | |
| SCHEMBL29072920 | 0.91 | SELL (0.75) | SELLSELPCYP1A2LDHAALDH1A1 | |
| SCHEMBL29208048 | 0.91 | SELL (0.75) | SELLSELPCYP1A2LDHAALDH1A1 | |
| SCHEMBL29112577 | 0.91 | SELL (0.75) | SELLSELPCYP1A2LDHAALDH1A1 | |
| SCHEMBL11043522 | 0.91 | SELL (0.75) | SELLSELPCYP1A2LDHAALDH1A1 | |
| SCHEMBL29250135 | 0.91 | SELL (0.75) | SELLSELPCYP1A2LDHAALDH1A1 | |
| SCHEMBL29072927 | 0.91 | SELL (0.75) | SELLSELPCYP1A2LDHAALDH1A1 | |
| SCHEMBL30936659 | 0.88 | SELL (0.71) | SELLSELPCYP1A2LDHAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106984190-B | Method for catalytic degradation of volatile organic compounds | 中能科泰（北京）科技有限公司 | 2020-07-10 | — | — | CN | disclosed |