Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.42 |
| ▸ | CA2 | P00918 | 9/20 | 0.42 |
| ▸ | CA9 | Q16790 | 8/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28424856 | 1.00 | CA1 (0.42) | CA1CA2CA9CA12CA7 | |
| SCHEMBL719166 | 0.86 | CA1 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL721790 | 0.86 | CA1 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1276367 | 0.86 | CA1 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL717340 | 0.86 | CA1 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL987798 | 0.83 | CA1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL723644 | 0.83 | CA1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1276368 | 0.83 | CA1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL987423 | 0.83 | CA1 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL1352869 | 0.81 | RECQL (0.56) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111249252-B | Albumin nanoparticle composition and preparation method thereof | 中国医学科学院医药生物技术研究所 | 2021-09-14 | — | — | CN | disclosed |
| CN-109998996-B | Lipid composition and method for improving antitumor activity of drug | 中国医学科学院医药生物技术研究所 | 2021-02-26 | — | — | CN | disclosed |
| CN-110054659-B | Method for improving antitumor activity of medicine | 中国医学科学院医药生物技术研究所 | 2020-09-11 | — | — | CN | disclosed |
| CN-111249252-A | Albumin nanoparticle composition and preparation method thereof | 中国医学科学院医药生物技术研究所 | 2020-06-09 | — | — | CN | disclosed |