Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952684 | 1.00 | EPHX2 (0.32) | EPHX2PPARGPPARA | |
| SCHEMBL211367 | 0.96 | ANO1 (0.32) | — | |
| SCHEMBL210838 | 0.94 | EPHX2 (0.33) | EPHX2PPARGPPARA | |
| SCHEMBL211927 | 0.91 | P2RX4 (0.33) | EPHX2 | |
| SCHEMBL210925 | 0.89 | ANO1 (0.32) | EPHX2 | |
| SCHEMBL210167 | 0.87 | ANO1 (0.31) | — | |
| SCHEMBL2837660 | 0.86 | P2RX4 (0.33) | — | |
| SCHEMBL211368 | 0.85 | CTSK (0.32) | — | |
| SCHEMBL211948 | 0.85 | ABL1 (0.30) | — | |
| SCHEMBL210728 | 0.85 | CTSK (0.33) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195328-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Incorporated (US) | 2010-06-16 | — | — | EP | disclosed |