Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.41 |
| ▸ | ITK | Q08881 | 3/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28384405 | 0.96 | EGFR (0.42) | EGFRITKJAK3BTKFGFR1 | |
| SCHEMBL28420729 | 0.93 | EGFR (0.43) | EGFRITKBTKFGFR1KDR | |
| SCHEMBL28387956 | 0.93 | EGFR (0.45) | EGFR | |
| SCHEMBL28385580 | 0.90 | FGFR1 (0.46) | EGFRITKBTKFGFR1KDR | |
| SCHEMBL28386199 | 0.87 | EGFR (0.38) | EGFRITKJAK3BTK | |
| SCHEMBL28387187 | 0.87 | FGFR1 (0.52) | EGFRFGFR1KDR | |
| SCHEMBL28383470 | 0.86 | JAK3 (0.47) | EGFRJAK3 | |
| SCHEMBL28416830 | 0.85 | EGFR (0.39) | EGFRITK | |
| SCHEMBL28418732 | 0.85 | EGFR (0.41) | EGFRJAK3 | |
| SCHEMBL28387192 | 0.85 | BTK (0.46) | EGFRITKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285813-A | Chemical entities, compositions, and methods | 润新生物公司 | 2020-06-16 | — | — | CN | disclosed |